Bring a large pot of salted water to a boil. Add the 12 oz ziti pasta and cook according to package instructions until al dente (usually about 9-11 minutes). Drain the pasta and set aside.
In a large mixing bowl, combine 2 cups Alfredo sauce, 1/2 cup softened cream cheese, 1/2 teaspoon garlic powder, 1/2 teaspoon Italian seasoning, and 1/4 teaspoon black pepper. Stir until smooth and well blended.
Fold in 2 cups diced cooked chicken and 1 cup grated Parmesan cheese to the sauce mixture. Then add the cooked ziti and gently toss everything together until the pasta is evenly coated.
Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish with olive oil or cooking spray. Pour the pasta mixture into the dish and spread it out evenly.
Sprinkle 1 cup shredded mozzarella cheese evenly over the top of the ziti.
Bake in the preheated oven for 20-25 minutes, or until the cheese is melted, bubbly, and slightly golden on top.
Remove from the oven and sprinkle 1/4 cup chopped fresh parsley over the top for a pop of color and freshness. Serve warm and enjoy the cheesy goodness!